Key Messages
Exploring The Potential Of Genetic Design: A Guide To Evolutionary Biology And The Latest Gene Technology
The secrets of the human genome are being revealed, and a revolution fueled by genetic engineering is on our doorstep.
In the near future, it will be possible to walk into a fertility clinic and reduce the chances that your child may even develop diseases such as Alzheimer’s disease and cancer in their lifetime.
On top of this, you could even have an impact on their characteristics such as height, intelligence, and personality.
If you’re curious about where we are in terms of gene technology and what this means for our future generations, then it’s time to dive into Hacking Darwin by Jamie Metzl.
Here you’ll learn about the history of evolutionary biology and genetics dating back to Darwin’s evolutionary theory alongside new discoveries that lay out a path for exciting possibilities within gene technology: from skin-tone manipulation to soon dispelling hereditary disease.
Discover how this revolution can improve the quality of life for ourselves, our children and generations after us.
Darwin And Mendel: How Evolutionary Theory And Genetics Explained Life On Earth
For hundreds of years, it was a commonly held belief that humans were placed on Earth by God and had not changed since then.
However, Charles Darwin challenged this assumption with his revolutionary book On the Origin of Species by Means of Natural Selection in 1859.
His research found that all life on Earth is related and had descended from a common ancestor.
Darwin determined that species evolved over time due to heritable traits which enabled them to compete and survive in their environment.
This process, which he called natural selection, meant that living creatures with more advantageous traits would live longer and reproduce more often than those with less advantageous traits.
Until now, humanity has been evolving through this natural selection of survivable/heritable traits for millions of years.
This theory was further expanded upon when Gregor Mendel found that individual traits are passed on independently from each other in pairs via genes inherited from each parent plant or animal.
Through this discovery, he concluded that an offspring’s genes are inherited as distinct units rather than being a product solely of its parents’ genetic makeup.
With the combination science of Darwinian evolutionary theory and Mendelian genetics, we are now entering a new era beyond natural selection in understanding the biology behind how humanity has developed over centuries.
Unlocking The Secrets Of The Genome: How We Decoded Our Genetic Code And What Comes Next
Thanks to advancements in artificial intelligence and big data analytics, our biology is becoming another form of information technology.
With the discovery of genetic code, scientists were able to identify our unique units of genetic code known as genes which contain instructions for our cells to produce proteins – the building blocks of life.
The Human Genome Project launched in 1990 was an international effort to sequence the first human genome and it cost roughly $2.7 billion.
In just a few decades, private efforts have propelled the field forward with artificial intelligence (AI) powered databases now available that synthesize genomic information and run algorithms to analyze patterns.
That means scientists are now able to identify specific genes and further our understanding of the human genome – allowing us to literally ‘hack’ our own biology!
How Our Ability To Select Embryos Is Revolutionizing Reproductive Technology
Advances in assisted reproductive technologies (ART) have revolutionised the way that diseases, such as Tay-Sachs, are prevented and eventually eradicated.
With the invention of in vitro fertilization (IVF)s, and the subsequent successful execution of preimplantation genetic diagnosis (PGD) procedures, it then became possible to scan embryos for a range of single-gene mutation disorders.
However, over time we can expect this technology to become increasingly advanced.
It is predicted that within 10 years there will be further development in embryo screening for traits such as height, intelligence and personality as opposed to just disease.
Though this may seem like some far-out futuristic technology at present moment, it has already become accepted in some countries with gender selection entering 9 percent of PGT procedures in America.
As our medical understanding grows and develops so too will our capabilities with assisted reproductive technologies – from being able to check for binary options regarding complex diseases, to more sophisticated probabilities linking genes to particular traits , all while still considering ethics and risk management carefully so we can understand exactly how much control is given agents who select prospective offspring’s characteristics
We’Re At A Point Where We Can No Longer Deny Assisted Reproductive Technology’S Benefits And It’S Potential To Overtake Traditional Procreation
In Hacking Darwin, author megenomicist Jamie Metzl predicts that around 2045, IVF will surpass sex as the primary method of reproduction in the United States.
Currently, approximately 1.5% of all births in the US use IVF, but this could grow exponentially due to a variety of factors.
The rise in acceptance of assisted reproductive technology has already been seen in older women and mothers with specific hereditary risks as well as same-sex couples who may not be able to conceive normally.
The technology also allows for certain genetic mutations to be avoided – something parents will increasingly opt for if it offers their children the best chance of a healthy life.
In addition, governments and insurance companies have an economic incentive to promote assisted reproduction since preventative care is often cheaper than treating diseases once they occur.
With increasing demand paired with technological advancements leading to cheaper procedures, IVF could become much more widespread by 2045 and replace traditional sexual reproduction as the primary reproductive method.
The Ethical Challenges Of Manipulating The Human Genome
Rapid developments in genetic engineering suggest a future with immense possibilities.
Scientists are now able to edit, engineer and even create life through the use of advanced technology.
One example of this is embryo selection, which enables prospective parents to pick out an embryo based on its genetic makeup prior to implantation.
The biggest leap forward has been made possible by CRISPR, a bacterial system that works like tiny molecular scissors to cut DNA at precise locations.
Gene-editing has led to breakthroughs such in healthcare, like CAR-T therapy – a gene therapy used for cancer – which saw 83 percent of its clinical trial patients seeing cancer go into remission.
But gene-editing isn’t just limited to healthcare advances; scientists have already started experimenting with altering genes outside of the medical field, like changing flowers from purple to white.
This same technology could be used one day to give humans physical traits that don’t exist today, such as heat-resistant skin or eagle vision.
In addition, synthetic biology is opening up new questions about how genetic code can be written from scratch and used for new traits that don’t exist yet.
It’s clear that our understanding about the intersection between science and technology continues to evolve quickly, leading us into ever new opportunities and ethical questions for humanity currently hard for us to conceive or answer.
The Global Impact Of Rejection Of Cultural Diversity: How Human Competition Is Driving The Genetic Revolution
The genetic revolution is here and it’s undeniable that people won’t necessarily come up with the same opinion when it comes to genetic technology.
We’re seeing this right now in the divide over genetically modified crops: some countries allow their farming industry to use GM seeds, others have put a ban in place fearing the unknown consequences.
Similarly, polls on genetic engineering around the world show that opinions differ on whether or not they believe these advancements are beneficial or dangerous.
For example, Americans seem to be more open with manipulating genes as a means of preventing diseases, while countries with Catholic leanings like Austria generally oppose prenatal testing and gene-editing research.
And then of course there’s individual opinion: In the Jewish community for instance, gene manipulation was quickly adopted in order to battle Tay-Sachs despite any objections.
It was seen by some scholars as an act of kindness for the betterment of humanity – something that could never have been achieved without genetic alteration!
Ultimately, no one knows what will happen once everyone starts taking part in this newfangled technology – but if we go off current evidence, we can safely assume that when it comes to opinions on the genetics revolution our society as a whole, nations included, will struggle to come up with one consensus agreement.
The Genetic Arms Race: What We Need To Consider Before Embracing The Future Of Humanity Through Genetic Engineering
Hacking Darwin outlines how competition will drive the genetic revolution forward.
Countries like Russia, China, and the United States are sponsoring genetic athletes for international competitions such as the Olympics.
The advancement of technology means that genetic editing of adult athletes could soon become possible, to produce better performance.
Naturally, this poses challenges when it comes to curtailing unfair advantages in international sporting competitions.
We can see examples of countries using genes to increase athletic abilities today – parents in the US can check athletic aptitude with genome testing, Uzbekistan has its national sports program based on gene testing and even the Chinese announced that selection for Winter Olympics 2022 will include a round of genetic sequencing.
The USA and China have muscled their way into a global contest for power through leveraging advances related to genetics engineering – President Jinping desires China to become a dominant force in technological progress, while budget cuts and stalling developments are slowing down innovation from the United States side.
The ethical implications regarding competition over genes should not be overlooked – diverting too far from ideals might lead us into a future not many would like — where genetical alterations make certain citizens taller and smarter than others, possibly leading all the way up to a frightening new level of warfare – things we must avoid at any cost if we want humanity’s future to remain bright.
We Must Work To Celebrate Diversity And Address Inequality Today In Order To Prevent A Genetically Enhanced Monoculture Of The Future
As we enter the genetic revolution, there are numerous ethical questions that must be addressed.
One of the most important is how this technology will affect diversity and equality in our societies.
It’s all too easy to imagine a world where certain sexual orientations or skin colors are considered more desirable than others – leading to a homogenous mono-culture.
On the other hand, allowing people to alter their offspring’s genes could create top-down class divides and further inequality between those who can afford it and those who can’t.
At present, the potential implications of using reproductive technologies remains largely unknown and requires open conversations to ensure that our future world embraces, rather than suppresses, diversity.
Careful consideration must also be given to our current context in which inequalities already exist on both an environmental and genetic level.
Ultimately, if used responsibly, these technologies have the potential to do some tremendous good – from curing fatal diseases to eliminating physical disabilities or enhancing talents.
As such, it’s important that we approach this revolution with caution but also a deep understanding of its positive potentials as well as how it can help combat existing forms of inequality today.
We Must Actively Educate Ourselves And Others On Genetics To Empower The Future Of Humanity
Public education and regulation of reproductive technologies are absolutely essential for avoiding a catastrophe in the future.
We have seen this with nuclear weapons, where an international treaty like the Non-Proliferation of Nuclear Weapons (NPT) has managed to prevent a full-scale nuclear war but has not prevented countries from acquiring nuclear weapons or technologies.
If we want to avoid a similar disaster with reproductive technologies, it is vital that each country creates their own public-education program and regulatory framework, as well as engaging in global dialogue regarding ethical concerns.
Countries like the United Kingdom have already taken steps in this direction by setting up bodies such as the Department of Health’s Human Fertilisation and Embryology Authority who are setting precedents for how these new technologies should be regulated.
These efforts have lead to higher levels of approval amongst British populations for genetic selection and engineering, even when it comes to capability enhancements such as increased intelligence.
However, without an international body set up, no amount of public knowledge could save us from the potential devastations these technologies could bring about.
Hence, we must all make sure that we educate ourselves, our peers and our communities about genetics and the future if we wish to try and prevent any disasters from occurring in the first place.
Wrap Up
As the world moves closer to harnessing the power of AI and big-data analytics to make discoveries about the human genome, Hacking Darwin provides a clear summary of how such advancements may affect our future.
It is likely that reproductive technologies will be used with increased prevalence in order to cure hereditary diseases, along with parental instincts and international competition driving their universal adoption.
For this reason, it is important for individuals, nations, and the international community to create educational and regulatory bodies – so they can manage such changes responsibly – resulting in a brighter future.
In short, Hacking Darwin helps paint a picture of what our potentially genetically-altered futures may look like.